The Bassik Lab at Stanford University (http://bassiklab.stanford.edu) is seeking a Life Science Research Professional2 to be an integral member of a research team that is developing novel genetic tools, including ultracomplex CRISPR/Cas9 libraries, to conduct genetic screens in a range of medically relevant areas, such as cancer, neurodegeneration and infectious disease. The goal of this work is to understand (1) the biology of cancer development and identify novel therapeutic drug targets, as well as to (2) understand how macrophage cells of the immune system recognize and destroy pathogens ranging from protein aggregates to tumor cells. Candidate must be willing to work in a research team, be organized, enjoy problem solving, and have strong communication skills. This is a fantastic opportunity for a motivated, creative, and reliable person to participate in highly collaborative, cutting-edge research at the forefront of modern biology, with real world applications to develop new therapeutics to improve human health.

Responsibilities include cell culture and maintenance of human cell lines, basic molecular biology (PCR, cloning, running DNA and protein gels), flow cytometry, preparation of samples for deep sequencing, confocal microscopy, basic statistical calculations, and other duties as assigned. The LSRP will be expected to work closely with the PI to develop protocols, interpret and analyze the results of experiments, and suggest modifications to procedures as appropriate. The position includes lab management tasks such as ordering supplies, maintaining lab records, and adhering to safety regulations. The LSRP is expected to keep abreast of scientific literature and contribute new ideas and techniques to the lab, as well as attend lab meetings and journal clubs. There will be ample opportunity and encouragement for independent scientific development, project development, and paper writing for highly motivated candidates.

Duties include:

• Independently conduct a portion of the research project(s). Make recommendations on experimental design and/or research direction to principal investigator.
• Independently conduct complex (lab and/or field) experiments to gather data for a portion of a major research project.
• Interpret and analyze results, often where few guidelines exist, and make modifications to existing procedures and protocols.
• Develop new research protocols where appropriate protocols are not described in the literature or where modification or adaptation of standard procedures and protocols is required.
• Participate in multidisciplinary teams across different faculties or schools.
• Perform ongoing literature review to remain current with new procedures and related research; apply to ongoing research and development of new protocols.
• Contribute substantively to the preparation of papers for publication, especially in the results section, and to publication of findings. Present ongoing work to colleagues and/or academic conferences.
• Oversee supply and equipment budget under supervision of principal investigator or business manager.
• Work with health and safety department to ensure lab complies with regulations and all required trainings.
• Supervise (either formally or informally) staff or students as needed, including oversight and direction on techniques, as well as consultation on project work. Serve as a technical resource for other research staff.
• Oversee the daily activities of the laboratory including lab maintenance; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed. May assist with purchasing laboratory equipment.

*- Other duties may also be assigned.